A New OECD Definition for Per- and Polyfluoroalkyl Substances

The report presents a revised, broadly inclusive PFAS definition: “PFASs are defined as fluorinated substances that contain at least one fully fluorinated methyl or methylene carbon atom (without any H/Cl/Br/I atom attached to it), i.e., with a few noted exceptions, any chemical with at least a perfluorinated methyl group (−CF3) or a perfluorinated methylene group…

Half-lives of several polyfluoroalkyl substances (PFAS) in cattle serum and tissues

Cattle that were at steady-state serum polyfluoroalkyl substances (PFAS) concentrations due to several years of exposure to water contaminated by residues of Aqueous Film-Forming (AFFF) firefighting foam had perfluorooctane sulphonate (PFOS) isomers, perfluoroheptane sulphonate (PFHpS), perfluorohexane sulphonate (PFHxS), perfluorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA) in serum. Elimination serum half-lives were determined in five heifers…

Information Requirements under the Essential-Use Concept: PFAS Case Studies

This study investigates how much information is available on the types and functions of PFAS in these uses, how much information is available on alternatives to the use of PFAS in various products, their performance and hazardous properties and, finally, whether this information is sufficient as a basis for deciding on the essentiality of a…

Analysis of per- and poly-fluoroalkyl substances (PFAS) in processed foods from FDA’s Total Diet Study

The Food and Drug Administration’s (FDA) Total Diet Study (TDS) collects foods that are both nationally and regionally distributed. The study concludes that additional occurrence data are needed to better understand human exposure to per- and poly-fluoroalkyl substances (PFAS) from commercially available foods in the United States. August 31, 2021 | Analytical and Bioanalytical Chemistry